So a story line of someone starting with nothing, at the complete bottom, but rising to great power. That would be particularly interesting if its in a region where the rulers are oppressive or uninterested in the quality of life for the lower class. The rise of a benevolent leader that cares more about the quality of life for the lower classes than for improving his own quality of life.

Or this person could zone in on orphans and push for all orphans to be accepted into the homes of the wealthy. It would be an interesting development.

In response to your comment in general, I have wondered what the main "story" will be. If everyone is guided by the game engine to drive a central story, what kind of story are they looking to create? Peace/War, technological advancement, a large scale social experiment or human interactions with manufactured relationships?