I say the following as someone who has a job, and a life outside of the PC.
Casuals will be eaten alive in CoE. If you are a noble (like I am) you are in effect an absentee landlord. If you are in OPC mode when your domain is attacked by players you are screwed unless you have a support team around you who are not casual and are logged in. In which case why would they need you?
As for crafters and regular citizens same deal. OPC scripts will keep you alive but you will not advance your skills unless you are actively logged in. This means you will always be behind the skill curve. Those who are power gamers will always be the legendary level skill holders.
Anyone who says you don’t need to be logged in 40 hours a week to be on the bleeding edge or to work their way up the social ranking ladder is either naive or is flat out lying.
Now that said if you don’t want to be king, hold legendary status, or have a gamer guild around you who are power gamers you can still accomplish many great and fun things. You just have to temper your expectations.